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Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis
BACKGROUND: Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfuncti...
Autores principales: | Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke, Ramwadhdoebe, Tamara H., Semmelink, Johanna F., Maijer, Karen I., Zijlstra, IJsbrand A., Maas, Mario, Gerlag, Danielle M., Geijtenbeek, Teunis B. H., Tak, Paul P., Mebius, Reina E., van Baarsen, Lisa G. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828373/ https://www.ncbi.nlm.nih.gov/pubmed/29482663 http://dx.doi.org/10.1186/s13075-018-1529-8 |
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