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Correcting for 16S rRNA gene copy numbers in microbiome surveys remains an unsolved problem
The 16S ribosomal RNA gene is the most widely used marker gene in microbial ecology. Counts of 16S sequence variants, often in PCR amplicons, are used to estimate proportions of bacterial and archaeal taxa in microbial communities. Because different organisms contain different 16S gene copy numbers...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828423/ https://www.ncbi.nlm.nih.gov/pubmed/29482646 http://dx.doi.org/10.1186/s40168-018-0420-9 |