Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells

Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity and an autoantigen in the autoimmune blistering di...

Descripción completa

Detalles Bibliográficos
Autores principales: Kitashima, Daniela Y., Kobayashi, Tetsuro, Woodring, Therese, Idouchi, Kacey, Doebel, Thomas, Voisin, Benjamin, Adachi, Takeya, Ouchi, Takeshi, Takahashi, Hayato, Nishifuji, Koji, Kaplan, Daniel H., Clausen, Björn E., Amagai, Masayuki, Nagao, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828466/
https://www.ncbi.nlm.nih.gov/pubmed/29307572
http://dx.doi.org/10.1016/j.ebiom.2017.12.022

Ejemplares similares

Ejemplares similares