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Switching and loss of cellular cytokine producing capacity characterize in vivo viral infection and malignant transformation in human T- lymphotropic virus type 1 infection

Adult T-cell leukaemia/lymphoma (ATL) arises from chronic non-malignant human T lymphotropic virus type-1 (HTLV-1) infection which is characterized by high plasma pro-inflammatory cytokines whereas ATL is characterized by high plasma anti-inflammatory (IL-10) concentrations. The poor prognosis of AT...

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Detalles Bibliográficos
Autores principales:	Kagdi, Huseini, Demontis, Maria Antonietta, Ramos, Juan Carlos, Taylor, Graham P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828519/ https://www.ncbi.nlm.nih.gov/pubmed/29444188 http://dx.doi.org/10.1371/journal.ppat.1006861

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