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Passive Transfer of Immune Sera Induced by a Zika Virus-Like Particle Vaccine Protects AG129 Mice Against Lethal Zika Virus Challenge
Zika virus (ZIKV) poses a serious public health threat due to its association with birth defects in developing fetuses and Guillain-Barré Syndrome in adults. We are developing a ZIKV vaccine based on virus-like particles (VLPs) generated in transiently transfected HEK293 cells. The genetic construct...
Autores principales: | Espinosa, Diego, Mendy, Jason, Manayani, Darly, Vang, Lo, Wang, Chunling, Richard, Tiffany, Guenther, Ben, Aruri, Jayavani, Avanzini, Jenny, Garduno, Fermin, Farness, Peggy, Gurwith, Marc, Smith, Jon, Harris, Eva, Alexander, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828544/ https://www.ncbi.nlm.nih.gov/pubmed/29269041 http://dx.doi.org/10.1016/j.ebiom.2017.12.010 |
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