T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties

Despite inducing strong T cell responses, Mycobacterium tuberculosis (Mtb) infection fails to elicit protective immune memory. As such latently infected or successfully treated Tuberculosis (TB) patients are not protected against recurrent disease. Here, using a mouse model of aerosol Mtb infection,...

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Detalles Bibliográficos
Autores principales: Lindenstrøm, Thomas, Moguche, Albanus, Damborg, Mie, Agger, Else Marie, Urdahl, Kevin, Andersen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828549/
https://www.ncbi.nlm.nih.gov/pubmed/29249639
http://dx.doi.org/10.1016/j.ebiom.2017.12.004

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