Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells()

Airway mucus hyperproduction and fluid imbalance are important hallmarks of cystic fibrosis (CF), the most common life-shortening genetic disorder in Caucasians. Dysregulated expression and/or function of airway ion transporters, including cystic fibrosis transmembrane conductance regulator (CFTR) a...

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Detalles Bibliográficos
Autores principales: Kamei, Shunsuke, Fujikawa, Haruka, Nohara, Hirofumi, Ueno-Shuto, Keiko, Maruta, Kasumi, Nakashima, Ryunosuke, Kawakami, Taisei, Matsumoto, Chizuru, Sakaguchi, Yuki, Ono, Tomomi, Suico, Mary Ann, Boucher, Richard C., Gruenert, Dieter C., Takeo, Toru, Nakagata, Naomi, Li, Jian-Dong, Kai, Hirofumi, Shuto, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828551/
https://www.ncbi.nlm.nih.gov/pubmed/29289532
http://dx.doi.org/10.1016/j.ebiom.2017.12.025

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