Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection

Early diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has neve...

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Autores principales: Yu, Yuetian, Hu, Fupin, Zhu, Cheng, Chen, Erzhen, Lu, Liangjing, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828565/
https://www.ncbi.nlm.nih.gov/pubmed/29607230
http://dx.doi.org/10.1155/2018/3295605
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author Yu, Yuetian
Hu, Fupin
Zhu, Cheng
Chen, Erzhen
Lu, Liangjing
Gao, Yuan
author_facet Yu, Yuetian
Hu, Fupin
Zhu, Cheng
Chen, Erzhen
Lu, Liangjing
Gao, Yuan
author_sort Yu, Yuetian
collection PubMed
description Early diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has never been reported in the literature. We reported a 29-year-old systemic lupus erythematosus female with CR-Kp blood stream infection. We highlighted the identification by next generation sequencing and treatment according to synergy susceptibility testing in the case.
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spelling pubmed-58285652018-04-01 Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection Yu, Yuetian Hu, Fupin Zhu, Cheng Chen, Erzhen Lu, Liangjing Gao, Yuan Case Rep Infect Dis Case Report Early diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has never been reported in the literature. We reported a 29-year-old systemic lupus erythematosus female with CR-Kp blood stream infection. We highlighted the identification by next generation sequencing and treatment according to synergy susceptibility testing in the case. Hindawi 2018-01-23 /pmc/articles/PMC5828565/ /pubmed/29607230 http://dx.doi.org/10.1155/2018/3295605 Text en Copyright © 2018 Yuetian Yu et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yu, Yuetian
Hu, Fupin
Zhu, Cheng
Chen, Erzhen
Lu, Liangjing
Gao, Yuan
Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title_full Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title_fullStr Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title_full_unstemmed Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title_short Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
title_sort use of next generation sequencing and synergy susceptibility testing in diagnosis and treatment of carbapenem-resistant klebsiella pneumoniae blood stream infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828565/
https://www.ncbi.nlm.nih.gov/pubmed/29607230
http://dx.doi.org/10.1155/2018/3295605
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