Cargando…

Endocytosis as a stabilizing mechanism for tissue homeostasis

Cells in tissues communicate by secreted growth factors (GF) and other signals. An important function of cell circuits is tissue homeostasis: maintaining proper balance between the amounts of different cell types. Homeostasis requires negative feedback on the GFs, to avoid a runaway situation in whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adler, Miri, Mayo, Avi, Zhou, Xu, Franklin, Ruth A., Jacox, Jeremy B., Medzhitov, Ruslan, Alon, Uri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828590/ https://www.ncbi.nlm.nih.gov/pubmed/29429964 http://dx.doi.org/10.1073/pnas.1714377115

Ejemplares similares

Principles of Cell Circuits for Tissue Repair and Fibrosis
por: Adler, Miri, et al.
Publicado: (2020)

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
por: Ding, Yi, et al.
Publicado: (2018)

Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11
por: Kokotos, A. C., et al.
Publicado: (2018)

Individuality and slow dynamics in bacterial growth homeostasis
por: Susman, Lee, et al.
Publicado: (2018)

Wnt/β-catenin signaling regulates ependymal cell development and adult homeostasis
por: Xing, Liujing, et al.
Publicado: (2018)

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter
por: Bick, Alexander G., et al.
Publicado: (2017)

α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis
por: Su, Yi-Ting, et al.
Publicado: (2019)

Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis
por: Loerakker, Sandra, et al.
Publicado: (2018)

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis
por: Eguchi, Tomoya, et al.
Publicado: (2018)

Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis
por: Voskuhl, Rhonda R., et al.
Publicado: (2019)

Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis
por: Andreatta, Gabriele, et al.
Publicado: (2020)

Evolution of vertical and oblique transmission under fluctuating selection
por: Ram, Yoav, et al.
Publicado: (2018)

Entropic contribution to enhanced thermal stability in the thermostable P450 CYP119
por: Liu, Zhuo, et al.
Publicado: (2018)

Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off
por: Yu, Haoran, et al.
Publicado: (2018)

Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome
por: Walker, Ethan J., et al.
Publicado: (2019)

Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis
por: Eshaghi, Arman, et al.
Publicado: (2019)

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response
por: Tzeng, Stephany Y., et al.
Publicado: (2018)

FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation
por: Lee, Cheol-Jung, et al.
Publicado: (2020)

Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities
por: Unterhauser, Katrin, et al.
Publicado: (2019)

Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics
por: Yu, Haoran, et al.
Publicado: (2018)

Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer’s-associated amyloid beta peptide
por: Cater, Jordan H., et al.
Publicado: (2019)

Linking imaging to omics utilizing image-guided tissue extraction
por: Disselhorst, Jonathan A., et al.
Publicado: (2018)

Predicting microbial growth in a mixed culture from growth curve data
por: Ram, Yoav, et al.
Publicado: (2019)

A mechanism for temporary bioadhesion
por: Wunderer, Julia, et al.
Publicado: (2019)

Varroa destructor feeds primarily on honey bee fat body tissue and not hemolymph
por: Ramsey, Samuel D., et al.
Publicado: (2019)

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue
por: Serbulea, Vlad, et al.
Publicado: (2018)

Stimulus generalization as a mechanism for learning to trust
por: FeldmanHall, Oriel, et al.
Publicado: (2018)

Intracellular mechanisms of fungal space searching in microenvironments
por: Held, Marie, et al.
Publicado: (2019)

Hatchet ribozyme structure and implications for cleavage mechanism
por: Zheng, Luqian, et al.
Publicado: (2019)

Tissue-specific geometry and chemistry of modern and fossilized melanosomes reveal internal anatomy of extinct vertebrates
por: Rossi, Valentina, et al.
Publicado: (2019)

Risk-taking bias in human decision-making is encoded via a right–left brain push–pull system
por: Sacré, Pierre, et al.
Publicado: (2019)

Shift from androgen to estrogen action causes abdominal muscle fibrosis, atrophy, and inguinal hernia in a transgenic male mouse model
por: Zhao, Hong, et al.
Publicado: (2018)

Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling
por: Mori, Akio, et al.
Publicado: (2019)

Phytophthora palmivora establishes tissue-specific intracellular infection structures in the earliest divergent land plant lineage
por: Carella, Philip, et al.
Publicado: (2018)

Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to G(Alert)
por: Lee, Geoffrey, et al.
Publicado: (2018)

Structure-guided examination of the mechanogating mechanism of PIEZO2
por: Taberner, Francisco J., et al.
Publicado: (2019)

Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during Drosophila wing morphogenesis
por: Gui, Jinghua, et al.
Publicado: (2019)

Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks
por: Qu, Meng, et al.
Publicado: (2018)

Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria
por: Belliveau, Nathan M., et al.
Publicado: (2018)

Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane
por: Wang, Qi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_js5ojrnqf7flkigvk8ivvekkot