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Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm
Cysteinyl-leukotrienes (cys-LTs) are 5-lipoxygenase-derived lipid mediators involved in the pathogenesis and progression of inflammatory disorders, in particular asthma. We have previously found evidence linking these mediators to increased levels of proteolytic enzymes in tissue specimens of human...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828611/ https://www.ncbi.nlm.nih.gov/pubmed/29432192 http://dx.doi.org/10.1073/pnas.1717906115 |