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Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the No...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828675/ https://www.ncbi.nlm.nih.gov/pubmed/29492099 http://dx.doi.org/10.3332/ecancer.2018.805 |
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author | Abad-Licham, Milagros Galvez-Olortegui, Jose Astigueta, Juan Díaz-Plasencia, Juan |
author_facet | Abad-Licham, Milagros Galvez-Olortegui, Jose Astigueta, Juan Díaz-Plasencia, Juan |
author_sort | Abad-Licham, Milagros |
collection | PubMed |
description | OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016. RESULTS: A total of 332 patients were selected, with an average age of 54.77 years (range 13–90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%. CONCLUSIONS: FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy. |
format | Online Article Text |
id | pubmed-5828675 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-58286752018-02-28 Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru Abad-Licham, Milagros Galvez-Olortegui, Jose Astigueta, Juan Díaz-Plasencia, Juan Ecancermedicalscience Research OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016. RESULTS: A total of 332 patients were selected, with an average age of 54.77 years (range 13–90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%. CONCLUSIONS: FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy. Cancer Intelligence 2018-02-01 /pmc/articles/PMC5828675/ /pubmed/29492099 http://dx.doi.org/10.3332/ecancer.2018.805 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Abad-Licham, Milagros Galvez-Olortegui, Jose Astigueta, Juan Díaz-Plasencia, Juan Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title | Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title_full | Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title_fullStr | Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title_full_unstemmed | Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title_short | Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru |
title_sort | diagnostic validity of fine-needle capillary cytology in palpable tumours at the oncology institute of peru |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828675/ https://www.ncbi.nlm.nih.gov/pubmed/29492099 http://dx.doi.org/10.3332/ecancer.2018.805 |
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