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Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru

OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the No...

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Autores principales: Abad-Licham, Milagros, Galvez-Olortegui, Jose, Astigueta, Juan, Díaz-Plasencia, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828675/
https://www.ncbi.nlm.nih.gov/pubmed/29492099
http://dx.doi.org/10.3332/ecancer.2018.805
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author Abad-Licham, Milagros
Galvez-Olortegui, Jose
Astigueta, Juan
Díaz-Plasencia, Juan
author_facet Abad-Licham, Milagros
Galvez-Olortegui, Jose
Astigueta, Juan
Díaz-Plasencia, Juan
author_sort Abad-Licham, Milagros
collection PubMed
description OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016. RESULTS: A total of 332 patients were selected, with an average age of 54.77 years (range 13–90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%. CONCLUSIONS: FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy.
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spelling pubmed-58286752018-02-28 Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru Abad-Licham, Milagros Galvez-Olortegui, Jose Astigueta, Juan Díaz-Plasencia, Juan Ecancermedicalscience Research OBJECTIVE: To evaluate the diagnostic validity of fine-needle capillary cytology (FNCC) in palpable tumours. MATERIAL AND METHODS: A retrospective, single-tray, cross-sectional diagnostic test study was carried out. We reviewed the cytological reports of the case files of the Cytology Unit of the Northern Regional Institute of Neoplastic Diseases (IREN) from January 2012 to December 2016. RESULTS: A total of 332 patients were selected, with an average age of 54.77 years (range 13–90 years); 61.4% of patients were female. The most frequent anatomical sites were lymph nodes (49.7%), thyroid (13.3%), breast (12.3%) and soft tissues (11.4%). Twenty-five cytologies did not have a histological correlation and six showed an atypical result. In the lymph node study, the most frequent pathology was metastatic carcinoma (49.7%), followed by lymphoma (13.3%). The FNCC had a sensitivity of 99.55%, a specificity of 98.77%, a positive predictive value of 99.55% and a negative predictive value of 98.77%. The positive likelihood ratio was 80.63%. CONCLUSIONS: FNCC is a useful, safe, reliable and economical ambulatory technique with minimal complications and high diagnostic accuracy. Cancer Intelligence 2018-02-01 /pmc/articles/PMC5828675/ /pubmed/29492099 http://dx.doi.org/10.3332/ecancer.2018.805 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Abad-Licham, Milagros
Galvez-Olortegui, Jose
Astigueta, Juan
Díaz-Plasencia, Juan
Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title_full Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title_fullStr Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title_full_unstemmed Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title_short Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru
title_sort diagnostic validity of fine-needle capillary cytology in palpable tumours at the oncology institute of peru
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828675/
https://www.ncbi.nlm.nih.gov/pubmed/29492099
http://dx.doi.org/10.3332/ecancer.2018.805
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