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Receptor-Interacting Protein Kinases 1 and 3, and Mixed Lineage Kinase Domain-Like Protein Are Activated by Sublytic Complement and Participate in Complement-Dependent Cytotoxicity

The complement system participates in the pathogenesis of many diseases. Complement activation produces several active protein complexes and peptides, including the terminal C5b-9 complexes. It was reported that C5b-9 complexes insert into the plasma membrane and cause membrane perturbation, intrace...

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Detalles Bibliográficos
Autores principales: Lusthaus, Michal, Mazkereth, Niv, Donin, Natalie, Fishelson, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829068/
https://www.ncbi.nlm.nih.gov/pubmed/29527209
http://dx.doi.org/10.3389/fimmu.2018.00306