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Key Inflammatory Processes in Human NASH Are Reflected in Ldlr(−/−).Leiden Mice: A Translational Gene Profiling Study
Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic m...
Autores principales: | Morrison, Martine C., Kleemann, Robert, van Koppen, Arianne, Hanemaaijer, Roeland, Verschuren, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829089/ https://www.ncbi.nlm.nih.gov/pubmed/29527177 http://dx.doi.org/10.3389/fphys.2018.00132 |
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