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Synthesis of an Al(18)F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

BACKGROUND: Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the (68)Ga radionuclide. Previous methods to synthetize (18)F–labeled PSMA ligands with complexes [(18)F]AlF(2+) hav...

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Detalles Bibliográficos
Autores principales: Giglio, Javier, Zeni, Maia, Savio, Eduardo, Engler, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829129/
https://www.ncbi.nlm.nih.gov/pubmed/29503861
http://dx.doi.org/10.1186/s41181-018-0039-y

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