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Fast, sensitive method for trisaccharide biomarker detection in mucopolysaccharidosis type 1

Certain recessively inherited diseases result from an enzyme deficiency within lysosomes. In mucopolysaccharidoses (MPS), a defect in glycosaminoglycan (GAG) degradation leads to GAG accumulation followed by progressive organ and multiple system dysfunctions. Current methods of GAG analysis used to...

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Detalles Bibliográficos
Autores principales:	Makino, Elina, Klodnitsky, Helen, Leonard, John, Lillie, James, Lund, Troy C., Marshall, John, Nietupski, Jennifer, Orchard, Paul J., Miller, Weston P., Phaneuf, Clifford, Tietz, Drew, Varban, Mariet L., Donovan, Marissa, Belenki, Alexey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829143/ https://www.ncbi.nlm.nih.gov/pubmed/29487322 http://dx.doi.org/10.1038/s41598-018-22078-2

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