Immunologic targeting of CD30 eliminates tumourigenic human pluripotent stem cells, allowing safer clinical application of hiPSC-based cell therapy

Induced pluripotent stem cells (iPSCs) are promising candidate cells for cardiomyogenesis in the failing heart. However, teratoma/tumour formation originating from undifferentiated iPSCs contaminating the graft is a critical concern for clinical application. Here, we hypothesized that brentuximab ve...

Descripción completa

Detalles Bibliográficos
Autores principales: Sougawa, Nagako, Miyagawa, Shigeru, Fukushima, Satsuki, Kawamura, Ai, Yokoyama, Junya, Ito, Emiko, Harada, Akima, Okimoto, Kaori, Mochizuki-Oda, Noriko, Saito, Atsuhiro, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829260/
https://www.ncbi.nlm.nih.gov/pubmed/29487310
http://dx.doi.org/10.1038/s41598-018-21923-8

Ejemplares similares

Ejemplares similares