Cargando…

A G-protein pathway determines grain size in rice

Manipulating grain size is an effective strategy for increasing cereal yields. Here we identify a pathway composed of five subunits of the heterotrimeric G proteins that regulate grain length in rice. The Gβ protein is essential for plant survival and growth. Gα provides a foundation for grain size...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Shengyuan, Wang, Lei, Mao, Hailiang, Shao, Lin, Li, Xianghua, Xiao, Jinghua, Ouyang, Yidan, Zhang, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829277/
https://www.ncbi.nlm.nih.gov/pubmed/29487318
http://dx.doi.org/10.1038/s41467-018-03141-y
_version_ 1783302771680739328
author Sun, Shengyuan
Wang, Lei
Mao, Hailiang
Shao, Lin
Li, Xianghua
Xiao, Jinghua
Ouyang, Yidan
Zhang, Qifa
author_facet Sun, Shengyuan
Wang, Lei
Mao, Hailiang
Shao, Lin
Li, Xianghua
Xiao, Jinghua
Ouyang, Yidan
Zhang, Qifa
author_sort Sun, Shengyuan
collection PubMed
description Manipulating grain size is an effective strategy for increasing cereal yields. Here we identify a pathway composed of five subunits of the heterotrimeric G proteins that regulate grain length in rice. The Gβ protein is essential for plant survival and growth. Gα provides a foundation for grain size expansion. Three Gγ proteins, DEP1, GGC2 and GS3, antagonistically regulate grain size. DEP1 and GGC2, individually or in combination, increase grain length when in complex with Gβ. GS3, having no effect on grain size by itself, reduces grain length by competitively interacting with Gβ. By combining different G-protein variants, we can decrease grain length by up to 35% or increase it by up to 19%, which leads to over 40% decreasing to 28% increasing of grain weight. The wide existence of such a conserved system among angiosperms suggests a possible general predictable approach to manipulating grain/organ sizes.
format Online
Article
Text
id pubmed-5829277
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-58292772018-03-02 A G-protein pathway determines grain size in rice Sun, Shengyuan Wang, Lei Mao, Hailiang Shao, Lin Li, Xianghua Xiao, Jinghua Ouyang, Yidan Zhang, Qifa Nat Commun Article Manipulating grain size is an effective strategy for increasing cereal yields. Here we identify a pathway composed of five subunits of the heterotrimeric G proteins that regulate grain length in rice. The Gβ protein is essential for plant survival and growth. Gα provides a foundation for grain size expansion. Three Gγ proteins, DEP1, GGC2 and GS3, antagonistically regulate grain size. DEP1 and GGC2, individually or in combination, increase grain length when in complex with Gβ. GS3, having no effect on grain size by itself, reduces grain length by competitively interacting with Gβ. By combining different G-protein variants, we can decrease grain length by up to 35% or increase it by up to 19%, which leads to over 40% decreasing to 28% increasing of grain weight. The wide existence of such a conserved system among angiosperms suggests a possible general predictable approach to manipulating grain/organ sizes. Nature Publishing Group UK 2018-02-27 /pmc/articles/PMC5829277/ /pubmed/29487318 http://dx.doi.org/10.1038/s41467-018-03141-y Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sun, Shengyuan
Wang, Lei
Mao, Hailiang
Shao, Lin
Li, Xianghua
Xiao, Jinghua
Ouyang, Yidan
Zhang, Qifa
A G-protein pathway determines grain size in rice
title A G-protein pathway determines grain size in rice
title_full A G-protein pathway determines grain size in rice
title_fullStr A G-protein pathway determines grain size in rice
title_full_unstemmed A G-protein pathway determines grain size in rice
title_short A G-protein pathway determines grain size in rice
title_sort g-protein pathway determines grain size in rice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829277/
https://www.ncbi.nlm.nih.gov/pubmed/29487318
http://dx.doi.org/10.1038/s41467-018-03141-y
work_keys_str_mv AT sunshengyuan agproteinpathwaydeterminesgrainsizeinrice
AT wanglei agproteinpathwaydeterminesgrainsizeinrice
AT maohailiang agproteinpathwaydeterminesgrainsizeinrice
AT shaolin agproteinpathwaydeterminesgrainsizeinrice
AT lixianghua agproteinpathwaydeterminesgrainsizeinrice
AT xiaojinghua agproteinpathwaydeterminesgrainsizeinrice
AT ouyangyidan agproteinpathwaydeterminesgrainsizeinrice
AT zhangqifa agproteinpathwaydeterminesgrainsizeinrice
AT sunshengyuan gproteinpathwaydeterminesgrainsizeinrice
AT wanglei gproteinpathwaydeterminesgrainsizeinrice
AT maohailiang gproteinpathwaydeterminesgrainsizeinrice
AT shaolin gproteinpathwaydeterminesgrainsizeinrice
AT lixianghua gproteinpathwaydeterminesgrainsizeinrice
AT xiaojinghua gproteinpathwaydeterminesgrainsizeinrice
AT ouyangyidan gproteinpathwaydeterminesgrainsizeinrice
AT zhangqifa gproteinpathwaydeterminesgrainsizeinrice