Cargando…
Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients
AIM: To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations. METHODS: Ninety-nine kidney transplant recipients (KTRs) were assigned to interventional exercise (Group A; n = 52) and a usual care coho...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829451/ https://www.ncbi.nlm.nih.gov/pubmed/29507858 http://dx.doi.org/10.5500/wjt.v8.i1.13 |
_version_ | 1783302810648969216 |
---|---|
author | Roi, Giulio Sergio Mosconi, Giovanni Totti, Valentina Angelini, Maria Laura Brugin, Erica Sarto, Patrizio Merlo, Laura Sgarzi, Sergio Stancari, Michele Todeschini, Paola La Manna, Gaetano Ermolao, Andrea Tripi, Ferdinando Andreoli, Lucia Sella, Gianluigi Anedda, Alberto Stefani, Laura Galanti, Giorgio Di Michele, Rocco Merni, Franco Trerotola, Manuela Storani, Daniela Nanni Costa, Alessandro |
author_facet | Roi, Giulio Sergio Mosconi, Giovanni Totti, Valentina Angelini, Maria Laura Brugin, Erica Sarto, Patrizio Merlo, Laura Sgarzi, Sergio Stancari, Michele Todeschini, Paola La Manna, Gaetano Ermolao, Andrea Tripi, Ferdinando Andreoli, Lucia Sella, Gianluigi Anedda, Alberto Stefani, Laura Galanti, Giorgio Di Michele, Rocco Merni, Franco Trerotola, Manuela Storani, Daniela Nanni Costa, Alessandro |
author_sort | Roi, Giulio Sergio |
collection | PubMed |
description | AIM: To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations. METHODS: Ninety-nine kidney transplant recipients (KTRs) were assigned to interventional exercise (Group A; n = 52) and a usual care cohort (Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life (HRQoL) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities. RESULTS: Eighty-five KTRs completed the study (Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload (+13 W, P = 0.0003), V’O(2) peak (+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor (+12 kg, P = 0.0368), height in the countermovement jump (+1.9 cm, P = 0.0293) and decreased in Body Mass Index (-0.5 kg/m(2), P = 0.0013). HRQoL significantly improved in physical function (P = 0.0019), physical-role limitations (P = 0.0321) and social functioning scales (P = 0.0346). No improvements were found in Group B. CONCLUSION: Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities. |
format | Online Article Text |
id | pubmed-5829451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-58294512018-03-05 Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients Roi, Giulio Sergio Mosconi, Giovanni Totti, Valentina Angelini, Maria Laura Brugin, Erica Sarto, Patrizio Merlo, Laura Sgarzi, Sergio Stancari, Michele Todeschini, Paola La Manna, Gaetano Ermolao, Andrea Tripi, Ferdinando Andreoli, Lucia Sella, Gianluigi Anedda, Alberto Stefani, Laura Galanti, Giorgio Di Michele, Rocco Merni, Franco Trerotola, Manuela Storani, Daniela Nanni Costa, Alessandro World J Transplant Clinical Trials Study AIM: To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations. METHODS: Ninety-nine kidney transplant recipients (KTRs) were assigned to interventional exercise (Group A; n = 52) and a usual care cohort (Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life (HRQoL) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities. RESULTS: Eighty-five KTRs completed the study (Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload (+13 W, P = 0.0003), V’O(2) peak (+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor (+12 kg, P = 0.0368), height in the countermovement jump (+1.9 cm, P = 0.0293) and decreased in Body Mass Index (-0.5 kg/m(2), P = 0.0013). HRQoL significantly improved in physical function (P = 0.0019), physical-role limitations (P = 0.0321) and social functioning scales (P = 0.0346). No improvements were found in Group B. CONCLUSION: Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities. Baishideng Publishing Group Inc 2018-02-24 2018-02-24 /pmc/articles/PMC5829451/ /pubmed/29507858 http://dx.doi.org/10.5500/wjt.v8.i1.13 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Clinical Trials Study Roi, Giulio Sergio Mosconi, Giovanni Totti, Valentina Angelini, Maria Laura Brugin, Erica Sarto, Patrizio Merlo, Laura Sgarzi, Sergio Stancari, Michele Todeschini, Paola La Manna, Gaetano Ermolao, Andrea Tripi, Ferdinando Andreoli, Lucia Sella, Gianluigi Anedda, Alberto Stefani, Laura Galanti, Giorgio Di Michele, Rocco Merni, Franco Trerotola, Manuela Storani, Daniela Nanni Costa, Alessandro Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title | Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title_full | Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title_fullStr | Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title_full_unstemmed | Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title_short | Renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
title_sort | renal function and physical fitness after 12-mo supervised training in kidney transplant recipients |
topic | Clinical Trials Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829451/ https://www.ncbi.nlm.nih.gov/pubmed/29507858 http://dx.doi.org/10.5500/wjt.v8.i1.13 |
work_keys_str_mv | AT roigiuliosergio renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT mosconigiovanni renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT tottivalentina renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT angelinimarialaura renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT bruginerica renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT sartopatrizio renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT merlolaura renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT sgarzisergio renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT stancarimichele renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT todeschinipaola renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT lamannagaetano renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT ermolaoandrea renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT tripiferdinando renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT andreolilucia renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT sellagianluigi renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT aneddaalberto renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT stefanilaura renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT galantigiorgio renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT dimichelerocco renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT mernifranco renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT trerotolamanuela renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT storanidaniela renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients AT nannicostaalessandro renalfunctionandphysicalfitnessafter12mosupervisedtraininginkidneytransplantrecipients |