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PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation
Single cell whole-genome sequencing (scWGS) is providing novel insights into the nature of genetic heterogeneity in normal and diseased cells. However, the whole-genome amplification process required for scWGS introduces biases into the resulting sequencing that can confound downstream analysis. Her...
Autores principales: | Sherman, Maxwell A, Barton, Alison R, Lodato, Michael A, Vitzthum, Carl, Coulter, Michael E, Walsh, Christopher A, Park, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829578/ https://www.ncbi.nlm.nih.gov/pubmed/29186545 http://dx.doi.org/10.1093/nar/gkx1195 |
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