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PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation

Single cell whole-genome sequencing (scWGS) is providing novel insights into the nature of genetic heterogeneity in normal and diseased cells. However, the whole-genome amplification process required for scWGS introduces biases into the resulting sequencing that can confound downstream analysis. Her...

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Detalles Bibliográficos
Autores principales: Sherman, Maxwell A, Barton, Alison R, Lodato, Michael A, Vitzthum, Carl, Coulter, Michael E, Walsh, Christopher A, Park, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829578/
https://www.ncbi.nlm.nih.gov/pubmed/29186545
http://dx.doi.org/10.1093/nar/gkx1195

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