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The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity
Four different types (α(4), α′(2,) (αβ)(2) and ϵ(2)) of RNA-splicing endonucleases (EndAs) for RNA processing are known to exist in the Archaea. Only the (αβ)(2) and ϵ(2) types can cleave non-canonical introns in precursor (pre)-tRNA. Both enzyme types possess an insert associated with a specific lo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829648/ https://www.ncbi.nlm.nih.gov/pubmed/29346615 http://dx.doi.org/10.1093/nar/gky003 |