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Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel

When a stop codon is at the 80S ribosomal A site, there are six nucleotides (+4 to +9) downstream that are inferred to be occupying the mRNA channel. We examined the influence of these downstream nucleotides on translation termination success or failure in mammalian cells at the three stop codons. T...

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Detalles Bibliográficos
Autores principales:	Cridge, Andrew G, Crowe-McAuliffe, Caillan, Mathew, Suneeth F, Tate, Warren P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829715/ https://www.ncbi.nlm.nih.gov/pubmed/29325104 http://dx.doi.org/10.1093/nar/gkx1315

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