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Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center

Intracellular levels of reactive oxygen species (ROS) increase as a consequence of oxidative stress and represent a major source of damage to biomolecules. Due to its high cellular abundance RNA is more frequently the target for oxidative damage than DNA. Nevertheless the functional consequences of...

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Detalles Bibliográficos
Autores principales:	Willi, Jessica, Küpfer, Pascal, Evéquoz, Damien, Fernandez, Guillermo, Katz, Assaf, Leumann, Christian, Polacek, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829716/ https://www.ncbi.nlm.nih.gov/pubmed/29309687 http://dx.doi.org/10.1093/nar/gkx1308

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