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Regional cerebral effects of ketone body infusion with 3-hydroxybutyrate in humans: Reduced glucose uptake, unchanged oxygen consumption and increased blood flow by positron emission tomography. A randomized, controlled trial

Ketone bodies are neuroprotective in neurological disorders such as epilepsy. We randomly studied nine healthy human subjects twice—with and without continuous infusion of 3-hydroxybutyrate–to define potential underlying mechanisms, assessed regionally (parietal, occipital, temporal, cortical grey,...

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Detalles Bibliográficos
Autores principales: Svart, Mads, Gormsen, Lars C., Hansen, Jakob, Zeidler, Dora, Gejl, Michael, Vang, Kim, Aanerud, Joel, Moeller, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830038/
https://www.ncbi.nlm.nih.gov/pubmed/29489818
http://dx.doi.org/10.1371/journal.pone.0190556