Long non-coding RNA Gas5 regulates proliferation and apoptosis in HCS-2/8 cells and growth plate chondrocytes by controlling FGF1 expression via miR-21 regulation

BACKGROUND: LncRNA Gas5 is known to be a key control element during growth, differentiation and development in mammalian species. However, the role and function of Gas5 in growth plate chondrocytes has not been determined. METHODS: The overexpression and knockdown models of Gas5 and miR-21 in cells...

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Detalles Bibliográficos
Autores principales: Liu, Xiong, She, Yuqi, Wu, Hongrong, Zhong, Da, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830091/
https://www.ncbi.nlm.nih.gov/pubmed/29490650
http://dx.doi.org/10.1186/s12929-018-0424-6

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