Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila

Transcriptional silencing is a conserved process used by embryonic germ cells to repress somatic fate and maintain totipotency and immortality. In Drosophila, this transcriptional silencing is mediated by polar granule component (pgc). Here, we show that in the adult ovary, pgc is required for timel...

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Detalles Bibliográficos
Autores principales: Flora, Pooja, Schowalter, Sean, Wong-Deyrup, SiuWah, DeGennaro, Matthew, Nasrallah, Mohamad Ali, Rangan, Prashanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830152/
https://www.ncbi.nlm.nih.gov/pubmed/29198563
http://dx.doi.org/10.1016/j.ydbio.2017.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830152/
https://www.ncbi.nlm.nih.gov/pubmed/29198563
http://dx.doi.org/10.1016/j.ydbio.2017.11.014

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