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PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

OBJECTIVES: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

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Detalles Bibliográficos
Autores principales:	Lockney, Natalie A., Yang, T. Jonathan, Barron, David, Gelb, Emily, Gelblum, Daphna Y., Yorke, Ellen, Shi, Weiji, Zhang, Zhigang, Rimner, Andreas, Wu, Abraham J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830173/ https://www.ncbi.nlm.nih.gov/pubmed/29503876 http://dx.doi.org/10.1016/j.ctro.2017.11.002

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