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Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices

BACKGROUND: To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). METHODS: Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis...

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Autores principales: Rosentreter, André, Lappas, Alexandra, Widder, Randolf Alexander, Alnawaiseh, Maged, Dietlein, Thomas Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830326/
https://www.ncbi.nlm.nih.gov/pubmed/29486746
http://dx.doi.org/10.1186/s12886-018-0721-6
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author Rosentreter, André
Lappas, Alexandra
Widder, Randolf Alexander
Alnawaiseh, Maged
Dietlein, Thomas Stefan
author_facet Rosentreter, André
Lappas, Alexandra
Widder, Randolf Alexander
Alnawaiseh, Maged
Dietlein, Thomas Stefan
author_sort Rosentreter, André
collection PubMed
description BACKGROUND: To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). METHODS: Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis of the overlying scleral flap and conjunctiva after Baerveldt drainage device surgery. The defects were repaired by lateral displacement of the tube towards the sclera, with a slice of a CGM as a patch, covered by adjacent conjunctiva. RESULT: Successful, lasting closure (follow-up of 12 to 42 months) of the conjunctival defects was achieved without any side-effects or complications in all eight cases. CONCLUSIONS: Erosion of the drainage tube, creating buttonholes in the conjunctiva after implantation of glaucoma drainage devices, is a potentially serious problem. It can be managed successfully using a biodegradable CGM as a patch.
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spelling pubmed-58303262018-03-05 Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices Rosentreter, André Lappas, Alexandra Widder, Randolf Alexander Alnawaiseh, Maged Dietlein, Thomas Stefan BMC Ophthalmol Research Article BACKGROUND: To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM). METHODS: Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis of the overlying scleral flap and conjunctiva after Baerveldt drainage device surgery. The defects were repaired by lateral displacement of the tube towards the sclera, with a slice of a CGM as a patch, covered by adjacent conjunctiva. RESULT: Successful, lasting closure (follow-up of 12 to 42 months) of the conjunctival defects was achieved without any side-effects or complications in all eight cases. CONCLUSIONS: Erosion of the drainage tube, creating buttonholes in the conjunctiva after implantation of glaucoma drainage devices, is a potentially serious problem. It can be managed successfully using a biodegradable CGM as a patch. BioMed Central 2018-02-27 /pmc/articles/PMC5830326/ /pubmed/29486746 http://dx.doi.org/10.1186/s12886-018-0721-6 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Rosentreter, André
Lappas, Alexandra
Widder, Randolf Alexander
Alnawaiseh, Maged
Dietlein, Thomas Stefan
Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_full Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_fullStr Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_full_unstemmed Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_short Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
title_sort conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830326/
https://www.ncbi.nlm.nih.gov/pubmed/29486746
http://dx.doi.org/10.1186/s12886-018-0721-6
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