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Current applications of antibody microarrays

The concept of antibody microarrays is one of the most versatile approaches within multiplexed immunoassay technologies. These types of arrays have increasingly become an attractive tool for the exploratory detection and study of protein abundance, function, pathways, and potential drug targets. Due...

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Detalles Bibliográficos
Autores principales: Chen, Ziqing, Dodig-Crnković, Tea, Schwenk, Jochen M., Tao, Sheng-ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830343/
https://www.ncbi.nlm.nih.gov/pubmed/29507545
http://dx.doi.org/10.1186/s12014-018-9184-2
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author Chen, Ziqing
Dodig-Crnković, Tea
Schwenk, Jochen M.
Tao, Sheng-ce
author_facet Chen, Ziqing
Dodig-Crnković, Tea
Schwenk, Jochen M.
Tao, Sheng-ce
author_sort Chen, Ziqing
collection PubMed
description The concept of antibody microarrays is one of the most versatile approaches within multiplexed immunoassay technologies. These types of arrays have increasingly become an attractive tool for the exploratory detection and study of protein abundance, function, pathways, and potential drug targets. Due to the properties of the antibody microarrays and their potential use in basic research and clinical analytics, various types of antibody microarrays have already been developed. In spite of the growing number of studies utilizing this technique, few reviews about antibody microarray technology have been presented to reflect the quality and future uses of the generated data. In this review, we provide a summary of the recent applications of antibody microarray techniques in basic biology and clinical studies, providing insights into the current trends and future of protein analysis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12014-018-9184-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-58303432018-03-05 Current applications of antibody microarrays Chen, Ziqing Dodig-Crnković, Tea Schwenk, Jochen M. Tao, Sheng-ce Clin Proteomics Review The concept of antibody microarrays is one of the most versatile approaches within multiplexed immunoassay technologies. These types of arrays have increasingly become an attractive tool for the exploratory detection and study of protein abundance, function, pathways, and potential drug targets. Due to the properties of the antibody microarrays and their potential use in basic research and clinical analytics, various types of antibody microarrays have already been developed. In spite of the growing number of studies utilizing this technique, few reviews about antibody microarray technology have been presented to reflect the quality and future uses of the generated data. In this review, we provide a summary of the recent applications of antibody microarray techniques in basic biology and clinical studies, providing insights into the current trends and future of protein analysis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12014-018-9184-2) contains supplementary material, which is available to authorized users. BioMed Central 2018-02-28 /pmc/articles/PMC5830343/ /pubmed/29507545 http://dx.doi.org/10.1186/s12014-018-9184-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Chen, Ziqing
Dodig-Crnković, Tea
Schwenk, Jochen M.
Tao, Sheng-ce
Current applications of antibody microarrays
title Current applications of antibody microarrays
title_full Current applications of antibody microarrays
title_fullStr Current applications of antibody microarrays
title_full_unstemmed Current applications of antibody microarrays
title_short Current applications of antibody microarrays
title_sort current applications of antibody microarrays
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830343/
https://www.ncbi.nlm.nih.gov/pubmed/29507545
http://dx.doi.org/10.1186/s12014-018-9184-2
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