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Nrf2 inhibition affects cell cycle progression during early mouse embryo development

Brusatol, a quassinoid isolated from the fruit of Bruceajavanica, has recently been shown to inhibit nuclear factor erythroid 2-related factor 2 (Nrf2) via Keap1-dependent ubiquitination and proteasomal degradation or protein synthesis. Nrf2 is a transcription factor that regulates the cellular defe...

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Detalles Bibliográficos
Autores principales:	LIN, Ying, SUI, Liu-Cai, WU, Rong-Hua, MA, Ru-Jun, FU, Hai-Yan, XU, Juan-Juan, QIU, Xu-Hua, CHEN, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830358/ https://www.ncbi.nlm.nih.gov/pubmed/29249781 http://dx.doi.org/10.1262/jrd.2017-042

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