A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia

Primary therapy resistance is a major problem in acute myeloid leukemia treatment. We set out to develop a powerful and robust predictor for therapy resistance for intensively treated adult patients. We used two large gene expression data sets (n=856) to develop a predictor of therapy resistance, wh...

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Detalles Bibliográficos
Autores principales: Herold, Tobias, Jurinovic, Vindi, Batcha, Aarif M. N., Bamopoulos, Stefanos A., Rothenberg-Thurley, Maja, Ksienzyk, Bianka, Hartmann, Luise, Greif, Philipp A., Phillippou-Massier, Julia, Krebs, Stefan, Blum, Helmut, Amler, Susanne, Schneider, Stephanie, Konstandin, Nikola, Sauerland, Maria Cristina, Görlich, Dennis, Berdel, Wolfgang E., Wörmann, Bernhard J., Tischer, Johanna, Subklewe, Marion, Bohlander, Stefan K., Braess, Jan, Hiddemann, Wolfgang, Metzeler, Klaus H., Mansmann, Ulrich, Spiekermann, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830382/
https://www.ncbi.nlm.nih.gov/pubmed/29242298
http://dx.doi.org/10.3324/haematol.2017.178442

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