Single cell polarity in liquid phase facilitates tumour metastasis

Dynamic polarisation of tumour cells is essential for metastasis. While the role of polarisation during dedifferentiation and migration is well established, polarisation of metastasising tumour cells during phases of detachment has not been investigated. Here we identify and characterise a type of p...

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Detalles Bibliográficos
Autores principales: Lorentzen, Anna, Becker, Paul F., Kosla, Jan, Saini, Massimo, Weidele, Kathrin, Ronchi, Paolo, Klein, Corinna, Wolf, Monika J., Geist, Felix, Seubert, Bastian, Ringelhan, Marc, Mihic-Probst, Daniela, Esser, Knud, Roblek, Marko, Kuehne, Felix, Bianco, Gaia, O’Connor, Tracy, Müller, Quentin, Schuck, Kathleen, Lange, Sebastian, Hartmann, Daniel, Spaich, Saskia, Groß, Olaf, Utikal, Jochen, Haferkamp, Sebastian, Sprick, Martin R., Damle-Vartak, Amruta, Hapfelmeier, Alexander, Hüser, Norbert, Protzer, Ulrike, Trumpp, Andreas, Saur, Dieter, Vartak, Nachiket, Klein, Christoph A., Polzer, Bernhard, Borsig, Lubor, Heikenwalder, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830403/
https://www.ncbi.nlm.nih.gov/pubmed/29491397
http://dx.doi.org/10.1038/s41467-018-03139-6

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