Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice

Exposure to chronic stress or elevated glucocorticoid hormone levels in adult life has been associated with cognitive deficits and an increased risk for Alzheimer’s disease (AD). Since exposure to stress during early life enhances stress-responsiveness and lastingly affects cognition in adult life,...

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Detalles Bibliográficos
Autores principales: Lesuis, Sylvie L, Weggen, Sascha, Baches, Sandra, Lucassen, Paul J, Krugers, Harm J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830444/
https://www.ncbi.nlm.nih.gov/pubmed/29491368
http://dx.doi.org/10.1038/s41398-018-0101-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830444/
https://www.ncbi.nlm.nih.gov/pubmed/29491368
http://dx.doi.org/10.1038/s41398-018-0101-2

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