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Plasticity in Glioma Stem Cell Phenotype and Its Therapeutic Implication
The marked heterogeneity in glioblastoma (GBM) may be induced through dynamic differentiation and dedifferentiation process of glioma cells. The hypothesis that environmental stimuli induce these phenotypic changes, including dedifferentiation into the stem cell phenotype which contributes to the hi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japan Neurosurgical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830525/ https://www.ncbi.nlm.nih.gov/pubmed/29129882 http://dx.doi.org/10.2176/nmc.ra.2017-0089 |