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TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
Skeletal homeostasis requires the continued replenishment of the bone forming osteoblast from a mesenchymal stem cell (MSC) population, a process that has been shown to be mechanically regulated. However, the mechanisms by which a biophysical stimulus can induce a change in biochemical signaling, me...
Autores principales: | Corrigan, Michele A., Johnson, Gillian P., Stavenschi, Elena, Riffault, Mathieu, Labour, Marie-Noelle, Hoey, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830574/ https://www.ncbi.nlm.nih.gov/pubmed/29491434 http://dx.doi.org/10.1038/s41598-018-22174-3 |
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