Cargando…

Anthropometric measurements and survival after a prostate cancer diagnosis

BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study be...

Descripción completa

Detalles Bibliográficos
Autores principales: Farris, Megan S, Courneya, Kerry S, Kopciuk, Karen A, McGregor, S Elizabeth, Friedenreich, Christine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830594/
https://www.ncbi.nlm.nih.gov/pubmed/29235565
http://dx.doi.org/10.1038/bjc.2017.440
_version_ 1783303024335126528
author Farris, Megan S
Courneya, Kerry S
Kopciuk, Karen A
McGregor, S Elizabeth
Friedenreich, Christine M
author_facet Farris, Megan S
Courneya, Kerry S
Kopciuk, Karen A
McGregor, S Elizabeth
Friedenreich, Christine M
author_sort Farris, Megan S
collection PubMed
description BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study between 1997 and 2000 then a prospective cohort study between 2000 and 2002 where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes. Cox proportional hazards were used to examine these associations. RESULTS: Survival analyses suggested no clear pattern of associations between post-diagnosis anthropometric measurements and all-cause mortality, prostate-specific mortality, first recurrence/progression or new primary cancer. CONCLUSIONS: We did not find a significant trend relating anthropometrics to survival outcomes after prostate cancer diagnosis. Continued assessment of objective measurements of body composition over the life-course is warranted to determine true associations between anthropometrics and survival after prostate cancer.
format Online
Article
Text
id pubmed-5830594
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-58305942019-02-20 Anthropometric measurements and survival after a prostate cancer diagnosis Farris, Megan S Courneya, Kerry S Kopciuk, Karen A McGregor, S Elizabeth Friedenreich, Christine M Br J Cancer Epidemiology BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study between 1997 and 2000 then a prospective cohort study between 2000 and 2002 where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes. Cox proportional hazards were used to examine these associations. RESULTS: Survival analyses suggested no clear pattern of associations between post-diagnosis anthropometric measurements and all-cause mortality, prostate-specific mortality, first recurrence/progression or new primary cancer. CONCLUSIONS: We did not find a significant trend relating anthropometrics to survival outcomes after prostate cancer diagnosis. Continued assessment of objective measurements of body composition over the life-course is warranted to determine true associations between anthropometrics and survival after prostate cancer. Nature Publishing Group 2018-02-20 2017-12-12 /pmc/articles/PMC5830594/ /pubmed/29235565 http://dx.doi.org/10.1038/bjc.2017.440 Text en Copyright © 2018 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/4.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
spellingShingle Epidemiology
Farris, Megan S
Courneya, Kerry S
Kopciuk, Karen A
McGregor, S Elizabeth
Friedenreich, Christine M
Anthropometric measurements and survival after a prostate cancer diagnosis
title Anthropometric measurements and survival after a prostate cancer diagnosis
title_full Anthropometric measurements and survival after a prostate cancer diagnosis
title_fullStr Anthropometric measurements and survival after a prostate cancer diagnosis
title_full_unstemmed Anthropometric measurements and survival after a prostate cancer diagnosis
title_short Anthropometric measurements and survival after a prostate cancer diagnosis
title_sort anthropometric measurements and survival after a prostate cancer diagnosis
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830594/
https://www.ncbi.nlm.nih.gov/pubmed/29235565
http://dx.doi.org/10.1038/bjc.2017.440
work_keys_str_mv AT farrismegans anthropometricmeasurementsandsurvivalafteraprostatecancerdiagnosis
AT courneyakerrys anthropometricmeasurementsandsurvivalafteraprostatecancerdiagnosis
AT kopciukkarena anthropometricmeasurementsandsurvivalafteraprostatecancerdiagnosis
AT mcgregorselizabeth anthropometricmeasurementsandsurvivalafteraprostatecancerdiagnosis
AT friedenreichchristinem anthropometricmeasurementsandsurvivalafteraprostatecancerdiagnosis