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Anthropometric measurements and survival after a prostate cancer diagnosis
BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study be...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830594/ https://www.ncbi.nlm.nih.gov/pubmed/29235565 http://dx.doi.org/10.1038/bjc.2017.440 |
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author | Farris, Megan S Courneya, Kerry S Kopciuk, Karen A McGregor, S Elizabeth Friedenreich, Christine M |
author_facet | Farris, Megan S Courneya, Kerry S Kopciuk, Karen A McGregor, S Elizabeth Friedenreich, Christine M |
author_sort | Farris, Megan S |
collection | PubMed |
description | BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study between 1997 and 2000 then a prospective cohort study between 2000 and 2002 where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes. Cox proportional hazards were used to examine these associations. RESULTS: Survival analyses suggested no clear pattern of associations between post-diagnosis anthropometric measurements and all-cause mortality, prostate-specific mortality, first recurrence/progression or new primary cancer. CONCLUSIONS: We did not find a significant trend relating anthropometrics to survival outcomes after prostate cancer diagnosis. Continued assessment of objective measurements of body composition over the life-course is warranted to determine true associations between anthropometrics and survival after prostate cancer. |
format | Online Article Text |
id | pubmed-5830594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-58305942019-02-20 Anthropometric measurements and survival after a prostate cancer diagnosis Farris, Megan S Courneya, Kerry S Kopciuk, Karen A McGregor, S Elizabeth Friedenreich, Christine M Br J Cancer Epidemiology BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case–control study between 1997 and 2000 then a prospective cohort study between 2000 and 2002 where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes. Cox proportional hazards were used to examine these associations. RESULTS: Survival analyses suggested no clear pattern of associations between post-diagnosis anthropometric measurements and all-cause mortality, prostate-specific mortality, first recurrence/progression or new primary cancer. CONCLUSIONS: We did not find a significant trend relating anthropometrics to survival outcomes after prostate cancer diagnosis. Continued assessment of objective measurements of body composition over the life-course is warranted to determine true associations between anthropometrics and survival after prostate cancer. Nature Publishing Group 2018-02-20 2017-12-12 /pmc/articles/PMC5830594/ /pubmed/29235565 http://dx.doi.org/10.1038/bjc.2017.440 Text en Copyright © 2018 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/4.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ |
spellingShingle | Epidemiology Farris, Megan S Courneya, Kerry S Kopciuk, Karen A McGregor, S Elizabeth Friedenreich, Christine M Anthropometric measurements and survival after a prostate cancer diagnosis |
title | Anthropometric measurements and survival after a prostate cancer diagnosis |
title_full | Anthropometric measurements and survival after a prostate cancer diagnosis |
title_fullStr | Anthropometric measurements and survival after a prostate cancer diagnosis |
title_full_unstemmed | Anthropometric measurements and survival after a prostate cancer diagnosis |
title_short | Anthropometric measurements and survival after a prostate cancer diagnosis |
title_sort | anthropometric measurements and survival after a prostate cancer diagnosis |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830594/ https://www.ncbi.nlm.nih.gov/pubmed/29235565 http://dx.doi.org/10.1038/bjc.2017.440 |
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