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Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma

BACKGROUND: The epidermal growth factor receptor (EGFR)-targeted therapies have been tested in the clinic as treatments for head and neck squamous cell carcinoma (HNSCC). Owing to intrinsic or acquired resistance, EGFR-targeted therapies often lead to a low response rate and treatment failure. Inter...

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Detalles Bibliográficos
Autores principales:	Ma, Hailong, Jin, Shufang, Yang, Wenyi, Zhou, Ge, Zhao, Mei, Fang, Sijie, Zhang, Zhiyuan, Hu, Jingzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830595/ https://www.ncbi.nlm.nih.gov/pubmed/29348488 http://dx.doi.org/10.1038/bjc.2017.442

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