Targeting glioma stem‐like cell survival and chemoresistance through inhibition of lysine‐specific histone demethylase KDM2B

Glioblastoma (GBM) ranks among the most lethal cancers, with current therapies offering only palliation. Inter‐ and intrapatient heterogeneity is a hallmark of GBM, with epigenetically distinct cancer stem‐like cells (CSCs) at the apex. Targeting GSCs remains a challenging task because of their uniq...

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Detalles Bibliográficos
Autores principales: Staberg, Mikkel, Rasmussen, Rikke Darling, Michaelsen, Signe Regner, Pedersen, Henriette, Jensen, Kamilla Ellermann, Villingshøj, Mette, Skjoth‐Rasmussen, Jane, Brennum, Jannick, Vitting‐Seerup, Kristoffer, Poulsen, Hans Skovgaard, Hamerlik, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830623/
https://www.ncbi.nlm.nih.gov/pubmed/29360266
http://dx.doi.org/10.1002/1878-0261.12174

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