Cargando…

Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro

Vanishing white matter (VWM) is a genetic childhood white matter disorder, characterized by chronic as well as episodic, stress provoked, neurological deterioration. Treatment is unavailable and patients often die within a few years after onset. VWM is caused by recessive mutations in the eukaryotic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wisse, Lisanne E., ter Braak, Timo J., van de Beek, Malu-Clair, van Berkel, Carola G. M., Wortel, Joke, Heine, Vivi M., Proud, Chris G., van der Knaap, Marjo S., Abbink, Truus E. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830650/ https://www.ncbi.nlm.nih.gov/pubmed/29491431 http://dx.doi.org/10.1038/s41598-018-21885-x

Ejemplares similares

Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions
por: Wisse, Lisanne E., et al.
Publicado: (2017)

Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations
por: Slynko, Inna, et al.
Publicado: (2021)

Stem cell therapy for white matter disorders: don’t forget the microenvironment!
por: Dooves, Stephanie, et al.
Publicado: (2016)

Neuron‐specific translational control shift ensures proteostatic resilience during ER stress
por: Wolzak, Kimberly, et al.
Publicado: (2022)

Vanishing white matter: deregulated integrated stress response as therapy target
por: Abbink, Truus E. M., et al.
Publicado: (2019)

Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter
por: Leferink, Prisca S., et al.
Publicado: (2017)

Megalencephalic leukoencephalopathy with cysts: the Glialcam‐null mouse model
por: Bugiani, Marianna, et al.
Publicado: (2017)

Regional vulnerability of brain white matter in vanishing white matter
por: Man, Jodie H.K., et al.
Publicado: (2023)

Cortical Pathology in Vanishing White Matter
por: Man, Jodie H. K., et al.
Publicado: (2022)

Therapeutic potential of human stem cell transplantations for Vanishing White Matter: A quest for the Goldilocks graft
por: Hillen, Anne E. J., et al.
Publicado: (2022)

In vivo targeting of a variant causing vanishing white matter using CRISPR/Cas9
por: Hillen, Anne E.J., et al.
Publicado: (2022)

Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter
por: Dooves, Stephanie, et al.
Publicado: (2019)

Astrocyte Subtype Vulnerability in Stem Cell Models of Vanishing White Matter
por: Leferink, Prisca S., et al.
Publicado: (2019)

Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1
por: Witkamp, Diede, et al.
Publicado: (2022)

The involvement of astrocytes in early‐life adversity induced programming of the brain
por: Abbink, Maralinde R., et al.
Publicado: (2019)

The $^{191,193}$Hg and $^{191,193}$Au positon decays
por: Vieu, C, et al.
Publicado: (1976)

Ribosomal scanning on the 5′-untranslated region of the human immunodeficiency virus RNA genome
por: Berkhout, Ben, et al.
Publicado: (2011)

Axonal abnormalities in vanishing white matter
por: Klok, Melanie D., et al.
Publicado: (2018)

Focal lesions following intracerebral gene therapy for mucopolysaccharidosis IIIA
por: Bugiani, Marianna, et al.
Publicado: (2023)

Levels in $^{191}$Ir
por: Bäcklin, A, et al.
Publicado: (1971)

UFM1 founder mutation in the Roma population causes recessive variant of H-ABC
por: Hamilton, Eline M.C., et al.
Publicado: (2017)

Circularization of the HIV-1 RNA genome
por: Ooms, Marcel, et al.
Publicado: (2007)

Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms
por: van der Knaap, Marjo S., et al.
Publicado: (2017)

Genetic defects disrupting glial ion and water homeostasis in the brain
por: Min, Rogier, et al.
Publicado: (2018)

Structure of $^{191}$Pb from $\alpha$- and $\beta$-decay spectroscopy
por: Cocolios, T E, et al.
Publicado: (2010)

191st Council Dinner
por: Ordan, Julien Marius
Publicado: (2018)

LIN92#19.1
Publicado: (1993)

F191. THE GENETICS OF DRUG-RELATED MOVEMENT DISORDERS AN UMBRELLA REVIEW OF META-ANALYSES
por: van der Burg, Nadine, et al.
Publicado: (2018)

Fagottkonzert B-Dur KV 191 = Bassoon concerto in B♭ major K. 191
por: Mozart, Wolfgang Amadeus, 1756-1791
Publicado: (2006)

The availability of the primer activation signal (PAS) affects the efficiency of HIV-1 reverse transcription initiation
por: Ooms, Marcel, et al.
Publicado: (2007)

DDX5 potentiates HIV-1 transcription as a co-factor of Tat
por: Sithole, Nyaradzai, et al.
Publicado: (2020)

The low-energy structure of $^{191}$Ir
por: Malmskog, S G, et al.
Publicado: (1970)

191 Giving birth with COVID-19
por: Andrade, A., et al.
Publicado: (2022)

Health Tract, No. 191: Curiosities of Eating
Publicado: (1864)

Health Tract, No. 191: Curiosities of Eating
Publicado: (1865)

High spin states in $^{189,191,193}$Au
por: Gono, Y, et al.
Publicado: (1976)

Altered PLP1 splicing causes hypomyelination of early myelinating structures
por: Kevelam, Sietske H, et al.
Publicado: (2015)

Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication – a targeted small interfering RNA library screen using pseudotyped and WT HIV-1
por: Williams, Claire A., et al.
Publicado: (2015)

Cascade $\gamma$-decay of the $^{191}Os$ compound nucleus
por: Bondarenko, V A, et al.
Publicado: (1999)

Development of Novel (191)Pt-Labeled Hoechst33258: (191)Pt Is More Suitable than (111)In for Targeting DNA
por: Obata, Honoka, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h9nt9flrtpqicps0mfqm8bkosm