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State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes
Affective states influence decision-making under ambiguity in humans and other animals. Individuals in a negative state tend to interpret ambiguous cues more negatively than individuals in a positive state. We demonstrate that the fruit fly, Drosophila melanogaster, also exhibits state-dependent cha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830672/ https://www.ncbi.nlm.nih.gov/pubmed/29491031 http://dx.doi.org/10.1098/rsbl.2017.0779 |
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author | Deakin, Amanda Mendl, Michael Browne, William J. Paul, Elizabeth S. Hodge, James J. L. |
author_facet | Deakin, Amanda Mendl, Michael Browne, William J. Paul, Elizabeth S. Hodge, James J. L. |
author_sort | Deakin, Amanda |
collection | PubMed |
description | Affective states influence decision-making under ambiguity in humans and other animals. Individuals in a negative state tend to interpret ambiguous cues more negatively than individuals in a positive state. We demonstrate that the fruit fly, Drosophila melanogaster, also exhibits state-dependent changes in cue interpretation. Drosophila were trained on a Go/Go task to approach a positive (P) odour associated with a sugar reward and actively avoid a negative (N) odour associated with shock. Trained flies were then either shaken to induce a purported negative state or left undisturbed (control), and given a choice between: air or P; air or N; air or ambiguous odour (1 : 1 blend of P : N). Shaken flies were significantly less likely to approach the ambiguous odour than control flies. This ‘judgement bias’ may be mediated by changes in neural activity that reflect evolutionarily primitive affective states. We cannot say whether such states are consciously experienced, but use of this model organism's versatile experimental tool kit may facilitate elucidation of their neural and genetic basis. |
format | Online Article Text |
id | pubmed-5830672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-58306722018-03-13 State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes Deakin, Amanda Mendl, Michael Browne, William J. Paul, Elizabeth S. Hodge, James J. L. Biol Lett Animal Behaviour Affective states influence decision-making under ambiguity in humans and other animals. Individuals in a negative state tend to interpret ambiguous cues more negatively than individuals in a positive state. We demonstrate that the fruit fly, Drosophila melanogaster, also exhibits state-dependent changes in cue interpretation. Drosophila were trained on a Go/Go task to approach a positive (P) odour associated with a sugar reward and actively avoid a negative (N) odour associated with shock. Trained flies were then either shaken to induce a purported negative state or left undisturbed (control), and given a choice between: air or P; air or N; air or ambiguous odour (1 : 1 blend of P : N). Shaken flies were significantly less likely to approach the ambiguous odour than control flies. This ‘judgement bias’ may be mediated by changes in neural activity that reflect evolutionarily primitive affective states. We cannot say whether such states are consciously experienced, but use of this model organism's versatile experimental tool kit may facilitate elucidation of their neural and genetic basis. The Royal Society 2018-02 2018-02-28 /pmc/articles/PMC5830672/ /pubmed/29491031 http://dx.doi.org/10.1098/rsbl.2017.0779 Text en © 2018 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Animal Behaviour Deakin, Amanda Mendl, Michael Browne, William J. Paul, Elizabeth S. Hodge, James J. L. State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title | State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title_full | State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title_fullStr | State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title_full_unstemmed | State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title_short | State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes |
title_sort | state-dependent judgement bias in drosophila: evidence for evolutionarily primitive affective processes |
topic | Animal Behaviour |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830672/ https://www.ncbi.nlm.nih.gov/pubmed/29491031 http://dx.doi.org/10.1098/rsbl.2017.0779 |
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