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Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis
Swiprosin-1/Efhd2 (Efhd2) is highly expressed in the CNS during development and in the adult. EFHD2 is regulated by Ca(2+) binding, stabilizes F-actin, and promotes neurite extension. Previous studies indicated a dysregulation of EFHD2 in human Alzheimer's disease brains. We hypothesized a detr...
Autores principales: | Regensburger, Martin, Prots, Iryna, Reimer, Dorothea, Brachs, Sebastian, Loskarn, Sandra, Lie, Dieter Chichung, Mielenz, Dirk, Winner, Beate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830914/ https://www.ncbi.nlm.nih.gov/pubmed/29337116 http://dx.doi.org/10.1016/j.stemcr.2017.12.010 |
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