‘Big bang’ of B-cell development revealed

Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112–126) and Li and colleagues (pp. 96–111) in this issue of Genes & Development provide new and unprecedented insight...

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Detalles Bibliográficos
Autor principal: Murre, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830931/
https://www.ncbi.nlm.nih.gov/pubmed/29449365
http://dx.doi.org/10.1101/gad.311357.118
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author Murre, Cornelis
author_facet Murre, Cornelis
author_sort Murre, Cornelis
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description Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112–126) and Li and colleagues (pp. 96–111) in this issue of Genes & Development provide new and unprecedented insights into the genetic and epigenetic mechanisms that establish B-cell identity.
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spelling pubmed-58309312018-07-15 ‘Big bang’ of B-cell development revealed Murre, Cornelis Genes Dev Outlook Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112–126) and Li and colleagues (pp. 96–111) in this issue of Genes & Development provide new and unprecedented insights into the genetic and epigenetic mechanisms that establish B-cell identity. Cold Spring Harbor Laboratory Press 2018-01-15 /pmc/articles/PMC5830931/ /pubmed/29449365 http://dx.doi.org/10.1101/gad.311357.118 Text en © 2018 Murre; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Murre, Cornelis
‘Big bang’ of B-cell development revealed
title ‘Big bang’ of B-cell development revealed
title_full ‘Big bang’ of B-cell development revealed
title_fullStr ‘Big bang’ of B-cell development revealed
title_full_unstemmed ‘Big bang’ of B-cell development revealed
title_short ‘Big bang’ of B-cell development revealed
title_sort ‘big bang’ of b-cell development revealed
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830931/
https://www.ncbi.nlm.nih.gov/pubmed/29449365
http://dx.doi.org/10.1101/gad.311357.118
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