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Craniometaphyseal Dysplasia Mutations in ANKH Negatively Affect Human Induced Pluripotent Stem Cell Differentiation into Osteoclasts

We identified osteoclast defects in craniometaphyseal dysplasia (CMD) using an easy-to-use protocol for differentiating osteoclasts from human induced pluripotent stem cells (hiPSCs). CMD is a rare genetic bone disorder, characterized by life-long progressive thickening of craniofacial bones and abn...

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Detalles Bibliográficos
Autores principales:	Chen, I-Ping, Luxmi, Raj, Kanaujiya, Jitendra, Hao, Zhifang, Reichenberger, Ernst J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830990/ https://www.ncbi.nlm.nih.gov/pubmed/29056330 http://dx.doi.org/10.1016/j.stemcr.2017.09.016

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