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The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment

The spindle assembly checkpoint plays a pivotal role in preventing aneuploidy and transformation. Many studies demonstrate impairment of this checkpoint in cancer cells. While leukemia is frequently driven by transformed hematopoietic stem and progenitor cells (HSPCs), the biology of the spindle ass...

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Detalles Bibliográficos
Autores principales:	Brown, Andreas, Pospiech, Johannes, Eiwen, Karina, Baker, Darren J., Moehrle, Bettina, Sakk, Vadim, Nattamai, Kalpana, Vogel, Mona, Grigoryan, Ani, Geiger, Hartmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830991/ https://www.ncbi.nlm.nih.gov/pubmed/29056333 http://dx.doi.org/10.1016/j.stemcr.2017.09.017

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