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Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons
During development, axons spontaneously assemble into a fascicle to form nerves and tracts in the nervous system as they extend within a spatially constrained path. However, understanding of the axonal fascicle has been hampered by lack of an in vitro model system. Here, we report generation of a ne...
Autores principales: | Kawada, Jiro, Kaneda, Shohei, Kirihara, Takaaki, Maroof, Asif, Levi, Timothée, Eggan, Kevin, Fujii, Teruo, Ikeuchi, Yoshiho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831012/ https://www.ncbi.nlm.nih.gov/pubmed/29107592 http://dx.doi.org/10.1016/j.stemcr.2017.09.021 |
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