Default Patterning Produces Pan-cortical Glutamatergic and CGE/LGE-like GABAergic Neurons from Human Pluripotent Stem Cells

Default differentiation of human pluripotent stem cells has been promoted as a model of cortical development. In this study, a developmental transcriptome analysis of default-differentiated hPSNs revealed a gene expression program resembling in vivo CGE/LGE subpallial domains and GABAergic signaling...

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Detalles Bibliográficos
Autores principales: Floruta, Crina M., Du, Ruofei, Kang, Huining, Stein, Jason L., Weick, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831028/
https://www.ncbi.nlm.nih.gov/pubmed/29107596
http://dx.doi.org/10.1016/j.stemcr.2017.09.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831028/
https://www.ncbi.nlm.nih.gov/pubmed/29107596
http://dx.doi.org/10.1016/j.stemcr.2017.09.023

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