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New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life

BACKGROUND: Patients with Sjögren’s syndrome (SS) typically present clinically with xerostomia (dry mouth) because of progressive damage to the exocrine glands. We developed a new, low-dose pilocarpine/sodium alginate (LPA) solution with pilocarpine hydrochloride to inhibit systemic adverse effects...

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Detalles Bibliográficos
Autores principales: Watanabe, Machiko, Yamada, Chisato, Komagata, Yoshinori, Kikuchi, Hirotoshi, Hosono, Hiroyuki, Itagaki, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831212/
https://www.ncbi.nlm.nih.gov/pubmed/29507747
http://dx.doi.org/10.1186/s40780-018-0099-x