Cargando…

New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life

BACKGROUND: Patients with Sjögren’s syndrome (SS) typically present clinically with xerostomia (dry mouth) because of progressive damage to the exocrine glands. We developed a new, low-dose pilocarpine/sodium alginate (LPA) solution with pilocarpine hydrochloride to inhibit systemic adverse effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Machiko, Yamada, Chisato, Komagata, Yoshinori, Kikuchi, Hirotoshi, Hosono, Hiroyuki, Itagaki, Fumio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831212/ https://www.ncbi.nlm.nih.gov/pubmed/29507747 http://dx.doi.org/10.1186/s40780-018-0099-x

Ejemplares similares

P40 Dry eyes and a dry mouth: is it Sjögren’s syndrome?
por: Sen, Ethan S, et al.
Publicado: (2022)

An Update on the Lived Experience of Dry Mouth in Sjögren's Syndrome Patients
por: Ngo, Di Ying Joanna, et al.
Publicado: (2021)

Enhancement or Suppression of ACE Inhibitory Activity by a Mixture of Tea and Foods for Specified Health Uses (FOSHU) That Are Marketed as “Support for Normal Blood Pressure”
por: Murakami, Isao, et al.
Publicado: (2011)

The influence of dietary peptide inhibitors of angiotensin-converting enzyme on the hypotensive effects of enalapril
por: Watanabe, Machiko, et al.
Publicado: (2015)

Dysbiotic salivary microbiota in dry mouth and primary Sjögren’s syndrome patients
por: Rusthen, S., et al.
Publicado: (2019)

Design and Evaluation of Liposomal Formulation of Pilocarpine Nitrate
por: Rathod, S., et al.
Publicado: (2010)

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome
por: Błochowiak, Katarzyna, et al.
Publicado: (2016)

Saliva Metabolomics in Dry Mouth Patients with Head and Neck Cancer or Sjögren’s Syndrome
por: Hynne, Håvard, et al.
Publicado: (2022)

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials
por: Nikles, Jane, et al.
Publicado: (2013)

The association between oral dryness and use of dry-mouth interventions in Sjögren’s syndrome patients
por: Assy, Z., et al.
Publicado: (2021)

Prediction model for milk transfer of drugs by primarily evaluating the area under the curve using QSAR/QSPR
por: Maeshima, Tae, et al.
Publicado: (2023)

Pilocarpine
por: Griffiths, H. T.
Publicado: (1882)

The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study
por: Hsu, Chung-Yuan, et al.
Publicado: (2019)

Relationship between the effects of food on the pharmacokinetics of oral antineoplastic drugs and their physicochemical properties
por: Omachi, Fukiko, et al.
Publicado: (2019)

Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments
por: Maeshima, Tae, et al.
Publicado: (2021)

Pilocarpine Hydrochloride for the Treatment of Xerostomia in Patients with Sjögren's Syndrome in Taiwan—A Double-blind, Placebo-controlled Trial
por: Wu, Cheng-Han, et al.
Publicado: (2006)

Salivary Glands and Periodontal Changes in a Population of Sjögren's and Sicca Syndrome Treated by Pilocarpine: A Pilot Study
por: Depinoy, Thibaud, et al.
Publicado: (2020)

Pilocarpine in Ascites
por: Banerji, Haran Chunder
Publicado: (1885)

Pilocarpine Injection
Publicado: (1907)

Pilocarpin in Toothache
Publicado: (1886)

Pilocarpine in Uræmia
Publicado: (1880)

Pilocarpine for Deafness
Publicado: (1885)

Pilocarpin in Asthma
Publicado: (1881)

Use and efficacy of dry-mouth interventions in Sjögren’s disease patients and possible association with perceived oral dryness and patients’ discomfort
por: Assy, Z., et al.
Publicado: (2023)

Utility and effectiveness of Symbicort® Turbuhaler® (oral inhalation containing budesonide and formoterol) in a patient with severe asthma after permanent tracheostomy
por: Maeda, Kohhei, et al.
Publicado: (2018)

Safety and efficacy of an intra-oral electrostimulator for the relief of dry mouth in patients with chronic graft versus host disease: Case Series
por: Zadik, Yehuda, et al.
Publicado: (2014)

Interferons and Dry Eye in Sjögren’s Syndrome
por: Ogawa, Yoko, et al.
Publicado: (2018)

Pilocarpine in Skin Diseases
Publicado: (1891)

Uræmia Treated by Pilocarpin
Publicado: (1880)

Pilocarpine in the Pruritus of Pregnancy
Publicado: (1879)

Pilocarpine in Cutaneous Diseases
Publicado: (1881)

Ecbolic Action of Pilocarpin
por: Lagorio, A.
Publicado: (1885)

Pilocarpine in Bright’s Disease
Publicado: (1888)

Diphtheria, Muriate of Pilocarpine
Publicado: (1881)

The Action and Uses of Pilocarpine
Publicado: (1882)

Tear film microbiome in Sjogren’s and non-Sjogren’s aqueous deficiency dry eye
por: Pal, Spandita, et al.
Publicado: (2023)

Rebamipide and mosapride enhance pilocarpine-induced salivation
por: Urita, Yoshihisa, et al.
Publicado: (2009)

Managing Sjögren’s Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy
por: Coursey, Terry G, et al.
Publicado: (2014)

Comparing Tear Film Viscosity between Sjögren and Non-Sjögren Dry Eye Disease
por: Lai, Hung-Yin, et al.
Publicado: (2023)

Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth
por: Takesh, Thair, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qvt20tklsupancu1ci11ks2j7c