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Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells

BACKGROUND: Retinoic acid (RA) signaling has been identified as a key driver in male and female gamete development. The presence of RA is a critical step in the initiation of meiosis and is required for the production of competent oocytes from primordial germ cells. Meiosis has been identified as a...

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Detalles Bibliográficos
Autores principales: Dyce, Paul W., Tenn, Neil, Kidder, Gerald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831580/
https://www.ncbi.nlm.nih.gov/pubmed/29490681
http://dx.doi.org/10.1186/s13048-018-0390-3