Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison

We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active c...

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Detalles Bibliográficos
Autores principales: Mehta, Ravi Tejraj, Pareek, Anil, Purkait, Indranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831582/
https://www.ncbi.nlm.nih.gov/pubmed/29507752
http://dx.doi.org/10.1186/s40885-018-0089-1
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author Mehta, Ravi Tejraj
Pareek, Anil
Purkait, Indranil
author_facet Mehta, Ravi Tejraj
Pareek, Anil
Purkait, Indranil
author_sort Mehta, Ravi Tejraj
collection PubMed
description We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active controlled, phase 4, randomized trial” by Oh GC, et al. with interest. The authors aim to compare the efficacy of amlodipine or hydrochlorothiazide (HCTZ) with an ARB. However, we wish to highlight that chlorthalidone (CTD) is the evidence-based and recommended anti-hypertensive diuretic, and should replace HCTZ in the trial to effectively compare efficacy against the CCB amlodipine.
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spelling pubmed-58315822018-03-05 Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison Mehta, Ravi Tejraj Pareek, Anil Purkait, Indranil Clin Hypertens Letter to the Editor We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active controlled, phase 4, randomized trial” by Oh GC, et al. with interest. The authors aim to compare the efficacy of amlodipine or hydrochlorothiazide (HCTZ) with an ARB. However, we wish to highlight that chlorthalidone (CTD) is the evidence-based and recommended anti-hypertensive diuretic, and should replace HCTZ in the trial to effectively compare efficacy against the CCB amlodipine. BioMed Central 2018-03-01 /pmc/articles/PMC5831582/ /pubmed/29507752 http://dx.doi.org/10.1186/s40885-018-0089-1 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Mehta, Ravi Tejraj
Pareek, Anil
Purkait, Indranil
Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title_full Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title_fullStr Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title_full_unstemmed Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title_short Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
title_sort chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831582/
https://www.ncbi.nlm.nih.gov/pubmed/29507752
http://dx.doi.org/10.1186/s40885-018-0089-1
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AT purkaitindranil chlorthalidonenothydrochlorothiazideistherightdiureticforcomparison

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