Therapeutic and pharmaco-biological, dose-ranging multicentre trial to determine the optimal dose of TRAnexamic acid to reduce blood loss in haemorrhagic CESarean delivery (TRACES): study protocol for a randomised, double-blind, placebo-controlled trial

BACKGROUND: Postpartum haemorrhage (PPH) is the leading cause of maternal death worldwide. Tranexamic acid (TA), an antifibrinolytic drug, reduces bleeding and transfusion need in major surgery and trauma. In ongoing PPH following vaginal delivery, a high dose of TA decreases PPH volume and duration...

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Detalles Bibliográficos
Autores principales: Bouthors, Anne-Sophie, Hennart, Benjamin, Jeanpierre, Emmanuelle, Baptiste, Anne-Sophie, Saidi, Imen, Simon, Elodie, Lannoy, Damien, Duhamel, Alain, Allorge, Delphine, Susen, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831710/
https://www.ncbi.nlm.nih.gov/pubmed/29490682
http://dx.doi.org/10.1186/s13063-017-2420-7

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